Scyliorhinin II

CAS No. 112748-19-3

Scyliorhinin II ( )

Catalog No. M30549 CAS No. 112748-19-3

Scyliorhinin II, a cyclic Tachykinin peptide, is a potent NK3 receptor agonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 190 Get Quote
10MG 311 Get Quote
25MG 624 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote

Biological Information

  • Product Name
    Scyliorhinin II
  • Note
    Research use only, not for human use.
  • Brief Description
    Scyliorhinin II, a cyclic Tachykinin peptide, is a potent NK3 receptor agonist.
  • Description
    Scyliorhinin II, a cyclic Tachykinin peptide, is a potent NK3 receptor agonist.(In Vitro):Scyliorhinin II is a neurokinin-3 selective tachykinin receptor, with a Ki of 2.5 nM for neurokinin-3 (NK-3) receptor in rat cerebral cortex. Scyliorhinin II has little effect on NK-1 and NK-2 receptors, with Ki (NK-1 receptor)/Ki (NK-3 receptor) and Ki (NK-2 receptor)/Ki (NK-3 receptor) of 176 and 200.(In Vivo):Scyliorhinin II produces potent, dose-related reciprocal hindlimb scratching about equipotently with an ED50 of 0.08 nmol via intracerebroventricularly (i.c.v.) administration in mice.
  • Synonyms
  • Pathway
    GPCR/G Protein
  • Target
    Neurokinin Receptor
  • Recptor
    Ki: 2.5 nM (Neurokinin-3 receptor)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    112748-19-3
  • Formula Weight
    1851.1
  • Molecular Formula
    C77H119N21O26S3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Buck SH, et al. The dogfish peptides scyliorhinin I and scyliorhinin II bind with differential selectivity to mammalian tachykinin receptors. Eur J Pharmacol. 1987 Nov 24;144(1):109-11.
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