Scyliorhinin II

Research use only, not for human use.

Scyliorhinin II, a cyclic Tachykinin peptide, is a potent NK3 receptor agonist.

Scyliorhinin II, a cyclic Tachykinin peptide, is a potent NK3 receptor agonist.(In Vitro):Scyliorhinin II is a neurokinin-3 selective tachykinin receptor, with a Ki of 2.5 nM for neurokinin-3 (NK-3) receptor in rat cerebral cortex. Scyliorhinin II has little effect on NK-1 and NK-2 receptors, with Ki (NK-1 receptor)/Ki (NK-3 receptor) and Ki (NK-2 receptor)/Ki (NK-3 receptor) of 176 and 200.(In Vivo):Scyliorhinin II produces potent, dose-related reciprocal hindlimb scratching about equipotently with an ED50 of 0.08 nmol via intracerebroventricularly (i.c.v.) administration in mice.

GPCR/G Protein

Neurokinin Receptor

Ki: 2.5 nM (Neurokinin-3 receptor)

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112748-19-3

1851.1

C77H119N21O26S3

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years